Leaky Gut and Autoimmune Diseases - Research
Autoimmune diseases are characterized by tissue damage and loss of function due to an immune response that is directed against specific organs. This review is focused on the role of impaired intestinal barrier function on autoimmune
pathogenesis.
Oral immune therapy: targeting the systemic immune system via the gut immune system for the treatment of inflammatory bowel disease
Inflammatory bowel diseases (IBD) are associated with an altered systemic immune response leading to inflammation-mediated damage to the gut and other organs. Oral immune therapy is a method of systemic immune modulation via alteration of the gut immune system. It uses the inherit ability of the innate system of the gut to redirect the systemic innate and adaptive immune responses. Oral immune therapy is an attractive clinical approach to treat autoimmune and inflammatory disorders. It can induce immune modulation without immune suppression, has minimal toxicity and is easily administered.
Malnutrition and Gut Microbiota in Children
Malnutrition remains a global crisis, especially for young children. While lack of food and infections are key drivers, emerging research shows the gut microbiota also plays a major role. Diet strongly influences the development of gut bacteria, which in turn affects a child’s nutritional status. Breastfeeding shapes the infant gut by promoting beneficial bifidobacteria, while the introduction of solid foods increases microbial diversity. It is also becoming evident that initial feeding practices and their resulting impact on the gut microbiota of infants have both short- and long-term effects on health throughout life. These early feeding practices have lasting effects on gut health and may impact a child’s risk of malnutrition.
Bioactive compounds, nutritional profile and health benefits of colostrum: a review
Bovine colostrum is defined as first milk by milching animals responsible for providing the innate immunity to the neonatal and possess many immunoglobulins for preventing the calf from diseases. Colostrum consist of many bioactive compounds like proteins, enzymes, growth factors, immunoglobulins and nucleotides that provides several benefits to human health. Numerous clinical and pre-clinical studies have demonstrated the therapeutic benefits of the bovine colostrum. This review focusses on bioactive compounds, their health benefits, potential of colostrum for developing several health foods and prevention of respiratory and gastrointestinal tract disorders. Processing can also be done to extend shelf-life and extraction of bioactive constituents either as encapsulated or as extracts. The products derived from bovine colostrum are high-end supplements possessing high nutraceutical value.
Bovine colostrum: an emerging nutraceutical
Nutraceutical, a term combining the words
“nutrition” and “pharmaceuticals”, is a food or food
product that provides health benefits as an adjuvant or
alternative therapy, including the treatment and prevention of infectious diseases in children and adults. There is
emerging evidence that bovine colostrum (BC) may be
one of the promising nutraceuticals which can prevent
or mitigate various diseases in newborns and adults.
Immunity-related disorders are one of the leading causes
of mortality in the world. BC is rich in immunity, growth
and antimicrobial factors, which promote tissue growth
and the maturation of digestive tract and immune function in neonatal animals and humans.r providing the innate immunity to the neonatal and possess many immunoglobulins for preventing the calf from diseases. Colostrum consist of many bioactive compounds like proteins, enzymes, growth factors, immunoglobulins and nucleotides that provides several benefits to human health. Numerous clinical and pre-clinical studies have demonstrated the therapeutic benefits of the bovine colostrum. This review focusses on bioactive compounds, their health benefits, potential of colostrum for developing several health foods and prevention of respiratory and gastrointestinal tract disorders. Processing can also be done to extend shelf-life and extraction of bioactive constituents either as encapsulated or as extracts. The products derived from bovine colostrum are high-end supplements possessing high nutraceutical value.
Bovine Colostrum for Veterinary and Human Health Applications: A Critical Review
Bovine colostrum harbors a diverse array of bioactive components suitable for the development of functional foods, nutraceuticals, and pharmaceuticals with veterinary and human health applications. Bovine colostrum has a strong safety profile with applications across all age groups for health promotion and the amelioration of a variety of disease states. Increased worldwide milk production and novel processing technologies have resulted in substantial growth of the market for colostrum-based products. This review provides a synopsis of the bioactive components in bovine colostrum, the processing techniques used to produce high-value colostrum-based products, and recent studies utilizing bovine colostrum for veterinary and human health.